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Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54

The awakening of the gonadotrophic axis at puberty is the end-point of a complex cascade of sex developmental events that leads to the attainment of reproductive capacity. Recently, loss-of-function mutations of the gene encoding GPR54, the putative receptor for the KiSS-1-derived peptide metastin,...

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Detalhes bibliográficos
Main Authors: Navarro, VM, Fernández-Fernández, R, Castellano, JM, Roa, J, Mayen, A, Barreiro, ML, Gaytan, F, Aguilar, E, Pinilla, L, Dieguez, C, Tena-Sempere, M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665361/
https://ncbi.nlm.nih.gov/pubmed/15486019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.072298
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