Acute desensitization of GIRK current in rat atrial myocytes is related to K(+) current flow

We have investigated the acute desensitization of acetylcholine-activated GIRK current (I(K(ACh))) in cultured adult rat atrial myocytes. Acute desensitization of I(K(ACh)) is observed as a partial relaxation of current with a half-time of < 5 s when muscarinic M(2) receptors are stimulated by a...

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Detalhes bibliográficos
Main Authors: Bender, Kirsten, Wellner-Kienitz, Marie-Cécile, Bösche, Leif I, Rinne, Andreas, Beckmann, Christian, Pott, Lutz
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665358/
https://ncbi.nlm.nih.gov/pubmed/15459243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.072462
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