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Melatonin advances the circadian timing of EEG sleep and directly facilitates sleep without altering its duration in extended sleep opportunities in humans

The rhythm of plasma melatonin originating from the pineal gland and driven by the circadian pacemaker located in the suprachiasmatic nucleus is closely associated with the circadian (approximately 24 h) variation in sleep propensity and sleep spindle activity in humans. We investigated the contribu...

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Detalhes bibliográficos
Main Authors: Rajaratnam, Shantha M W, Middleton, Benita, Stone, Barbara M, Arendt, Josephine, Dijk, Derk-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665336/
https://ncbi.nlm.nih.gov/pubmed/15459246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.073742
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