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Defective respiratory amiloride-sensitive sodium transport predisposes to pulmonary oedema and delays its resolution in mice

Pulmonary oedema results from an imbalance between the forces driving fluid into the airspace and the biological mechanisms for its removal. In mice lacking the α-subunit of the amiloride-sensitive sodium channel (αENaC(−/−)), impaired sodium transport-mediated lung liquid clearance at birth results...

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Detalhes bibliográficos
Main Authors: Egli, Marc, Duplain, Hervé, Lepori, Mattia, Cook, Stéphane, Nicod, Pascal, Hummler, Edith, Sartori, Claudio, Scherrer, Urs
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665279/
https://ncbi.nlm.nih.gov/pubmed/15308680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.066704
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