Phosphorylated guanidinoacetate partly compensates for the lack of phosphocreatine in skeletal muscle of mice lacking guanidinoacetate methyltransferase

The effects of creatine (Cr) absence in skeletal muscle caused by a deletion of guanidinoacetate methyltransferase (GAMT) were studied in a knockout mouse model by in vivo (31)P magnetic resonance (MR) spectroscopy. (31)P MR spectra of hindleg muscle of GAMT-deficient (GAMT–/–) mice showed no phosph...

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Detalhes bibliográficos
Main Authors: Kan, Hermien E, Jan Renema, W Klaas, Isbrandt, Dirk, Heerschap, Arend
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665207/
https://ncbi.nlm.nih.gov/pubmed/15284341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.067926
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