Role of adenosine transport in gestational diabetes-induced l-arginine transport and nitric oxide synthesis in human umbilical vein endothelium

Gestational diabetes is associated with increased l-arginine transport and nitric oxide (NO) synthesis, and reduced adenosine transport in human umbilical vein endothelial cells (HUVEC). Adenosine increases endothelial l-arginine/NO pathway via A(2) purinoceptors in HUVEC from normal pregnancies. It...

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Detalhes bibliográficos
Main Authors: Vásquez, Gustavo, Sanhueza, Felipe, Vásquez, Rodrigo, González, Marcelo, Martín, Rody San, Casanello, Paola, Sobrevia, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665196/
https://ncbi.nlm.nih.gov/pubmed/15272035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.068288
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