Inhibition of endogenous HIF inactivation induces angiogenesis in ischaemic skeletal muscles of mice

Hypoxia-inducible factor (HIF) modulates transcriptional control of several genes involved in vascular growth and cellular metabolism. HIF activity can be enhanced by suppression of prolyl and asparaginyl hydroxylase activity by dimethyloxalylglycine (DMOG). We have compared the effects of DMOG trea...

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Detalhes bibliográficos
Main Authors: Milkiewicz, Malgorzata, Pugh, Christopher W, Egginton, Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Rapid Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665195/
https://ncbi.nlm.nih.gov/pubmed/15319416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.069757
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