Magnesium-inhibited, TRPM6/7-like channel in cardiac myocytes: permeation of divalent cations and pH-mediated regulation

Cardiac tissue expresses several TRP proteins as well as a Mg(2+)-inhibited, non-selective cation current (I(MIC)) that bears many characteristics of TRP channel currents. We used the whole-cell voltage clamp technique in pig and rat ventricular myocytes to characterize the permeation, blockage prop...

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Detalhes bibliográficos
Main Authors: Gwanyanya, Asfree, Amuzescu, Bogdan, Zakharov, Sergey I, Macianskiene, Regina, Sipido, Karin R, Bolotina, Victoria M, Vereecke, Johan, Mubagwa, Kanigula
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665187/
https://ncbi.nlm.nih.gov/pubmed/15272039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.067637
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