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Alternative splicing of N- and C-termini of a C. elegans ClC channel alters gating and sensitivity to external Cl(−) and H(+)
CLH-3 is a meiotic cell cycle-regulated ClC Cl(−) channel that is functionally expressed in oocytes of the nematode Caenorhabditis elegans. CLH-3a and CLH-3b are alternatively spliced variants that have identical intramembrane regions, but which exhibit striking differences in their N- and C-termini...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Blackwell Science Inc
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1664825/ https://ncbi.nlm.nih.gov/pubmed/14565992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.053165 |
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