Maternal melatonin selectively inhibits cortisol production in the primate fetal adrenal gland

We tested the hypothesis that in primates, maternal melatonin restrains fetal and newborn adrenal cortisol production. A functional G-protein-coupled MT1 membrane-bound melatonin receptor was detected in 90% gestation capuchin monkey fetal adrenals by (a) 2-[(125)I] iodomelatonin binding (K(d), 75.7...

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Detalhes bibliográficos
Main Authors: Torres-Farfan, Claudia, Richter, Hans G, Germain, Alfredo M, Valenzuela, Guillermo J, Campino, Carmen, Rojas-García, Pedro, Forcelledo, María Luisa, Torrealba, Fernando, Serón-Ferré, María
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664788/
https://ncbi.nlm.nih.gov/pubmed/14673186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.056465
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