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pH modulation of currents that contribute to the medium and slow afterhyperpolarizations in rat CA1 pyramidal neurones

We examined the effects of changes in pH(o) and pH(i) on currents contributing to the medium and slow afterhyperpolarizations (mI(AHP) and sI(AHP), respectively) in rat CA1 neurones. Reducing pH(o) from 7.4 to 6.7 inhibited mI(AHP) and sI(AHP) whereas increasing pH(o) to 7.7 augmented mI(AHP) and, t...

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Autores principales: Kelly, Tony, Church, John
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664771/
https://ncbi.nlm.nih.gov/pubmed/14608014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.051607
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