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Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores

BACKGROUND: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epitopes. For Class II MHC alleles, the binding groove is open at both ends, causing ambiguity in the positional alignment b...

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Hlavní autoři: Salomon, Jesper, Flower, Darren R
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664591/
https://ncbi.nlm.nih.gov/pubmed/17105666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-501
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