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Natural selection mapping of the warfarin-resistance gene

In theory, genes under natural selection can be revealed by unique patterns of linkage disequilibrium (LD) and polymorphism at physically linked loci. However, given the effects of recombination and mutation, the physical extent and persistence of LD patterns in natural populations is uncertain. To...

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Detalhes bibliográficos
Main Authors: Kohn, Michael H., Pelz, Hans-Joachim, Wayne, Robert K.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16644/
https://ncbi.nlm.nih.gov/pubmed/10884423
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