Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia

Calcineurin (CN), a calcium- and calmodulin-dependent protein phosphatase, plays a significant role in the central nervous system. Previously, we reported that forebrain-specific CN knockout mice (CN mutant mice) have impaired working memory. To further analyze the behavioral effects of CN deficienc...

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Autors principals: Miyakawa, Tsuyoshi, Leiter, Lorene M., Gerber, David J., Gainetdinov, Raul R., Sotnikova, Tatyana D., Zeng, Hongkui, Caron, Marc G., Tonegawa, Susumu
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC166425/
https://ncbi.nlm.nih.gov/pubmed/12851457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1432926100
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