Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media

Otitis media, a common and often recurrent bacterial infection of childhood, is a major reason for physician visits and the prescription of antimicrobials. Haemophilus influenzae is the cause of ≈20% of episodes of bacterial otitis media, but most strains lack the capsule, a factor known to play a c...

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Bibliografiske detaljer
Main Authors: Bouchet, Valérie, Hood, Derek W., Li, Jianjun, Brisson, Jean-Robert, Randle, Gaynor A., Martin, Adèle, Li, Zhong, Goldstein, Richard, Schweda, Elke K. H., Pelton, Stephen I., Richards, James C., Moxon, E. Richard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC166410/
https://ncbi.nlm.nih.gov/pubmed/12855765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1432026100
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