CD1d-restricted T cells regulate dendritic cell function and antitumor immunity in a granulocyte–macrophage colony-stimulating factor-dependent fashion

CD1d-restricted T cells contribute to tumor protection, but their precise roles remain unclear. Here we show that tumor cells engineered to secrete granulocyte–macrophage colony-stimulating factor induce the expansion of CD1d-restricted T cells through a mechanism that involves CD1d and macrophage i...

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Autori principali: Gillessen, Silke, Naumov, Yuri N., Nieuwenhuis, Edward E. S., Exley, Mark A., Lee, Frederick S., Mach, Nicolas, Luster, Andrew D., Blumberg, Richard S., Taniguchi, Masaru, Balk, Steven P., Strominger, Jack L., Dranoff, Glenn, Wilson, S. Brian
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC166406/
https://ncbi.nlm.nih.gov/pubmed/12847287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1033098100
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