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Peptide synthesis with a template-like RNA guide and aminoacyl phosphate adaptors

The genetic code is thought to have developed from an early system of RNA-dependent peptide synthesis. To investigate one kind of template-like peptide synthesis that might emerge from an RNA world, we constructed highly reactive aminoacyl phosphate oligonucleotides as adaptors that bound to RNA gui...

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Bibliographic Details
Main Authors: Tamura, Koji, Schimmel, Paul
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC166369/
https://ncbi.nlm.nih.gov/pubmed/12857953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1432909100
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