Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP

Myotubularin is a dual-specific phosphatase that dephosphorylates phosphatidylinositol 3-phosphate and phosphatidylinositol (3,5)-bisphosphate. Mutations in myotubularin result in the human disease X-linked myotubular myopathy, characterized by persistence of muscle fibers that retain an immature ph...

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Main Authors: Nandurkar, Harshal H., Layton, Meredith, Laporte, Jocelyn, Selan, Carly, Corcoran, Lisa, Caldwell, Kevin K., Mochizuki, Yasuhiro, Majerus, Philip W., Mitchell, Christina A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2003
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC166368/
https://ncbi.nlm.nih.gov/pubmed/12847286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1033097100
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