Role of Mammalian Rad54 in Telomere Length Maintenance

The homologous recombination (HR) DNA repair pathway participates in telomere length maintenance in yeast but its putative role at mammalian telomeres is unknown. Mammalian Rad54 is part of the HR machinery, and Rad54-deficient mice show a reduced HR capability. Here, we show that Rad54-deficient mi...

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Main Authors: Jaco, Isabel, Muñoz, Purificación, Goytisolo, Fermín, Wesoly, Joanna, Bailey, Susan, Taccioli, Guillermo, Blasco, María A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2003
Assuntos:
DNA Dynamics and Chromosome Structure
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC166323/
https://ncbi.nlm.nih.gov/pubmed/12897131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.16.5572-5580.2003
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