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Role of Mammalian Rad54 in Telomere Length Maintenance

The homologous recombination (HR) DNA repair pathway participates in telomere length maintenance in yeast but its putative role at mammalian telomeres is unknown. Mammalian Rad54 is part of the HR machinery, and Rad54-deficient mice show a reduced HR capability. Here, we show that Rad54-deficient mi...

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Published in:Mol Cell Biol
Main Authors: Jaco, Isabel, Muñoz, Purificación, Goytisolo, Fermín, Wesoly, Joanna, Bailey, Susan, Taccioli, Guillermo, Blasco, María A.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2003
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166323/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12897131/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.16.5572-5580.2003
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