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Structural Environment Dictates the Biological Significance of Heme-Responsive Motifs and the Role of Hsp90 in the Activation of the Heme Activator Protein Hap1

Heme-responsive motifs (HRMs) mediate heme regulation of diverse regulatory proteins. The heme activator protein Hap1 contains seven HRMs, but only one of them, HRM7, is essential for heme activation of Hap1. To better understand the molecular basis underlying the biological significance of HRMs, we...

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Hlavní autoři: Chul Lee, Hee, Hon, Thomas, Lan, Changgui, Zhang, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC166322/
https://ncbi.nlm.nih.gov/pubmed/12897155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.16.5857-5866.2003
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