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ΔNp73 Facilitates Cell Immortalization and Cooperates with Oncogenic Ras in Cellular Transformation In Vivo

TP73, despite significant homology to TP53, is not a classic tumor suppressor gene, since it exhibits upregulation of nonmutated products in human tumors and lacks a tumor phenotype in p73-deficient mice. We recently reported that an N-terminally truncated isoform, ΔNp73, is upregulated in breast an...

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Bibliografski detalji
Glavni autori: Petrenko, Oleksi, Zaika, Alexander, Moll, Ute M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC166317/
https://ncbi.nlm.nih.gov/pubmed/12897129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.16.5540-5555.2003
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