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HSP27 Is a Ubiquitin-Binding Protein Involved in I-κBα Proteasomal Degradation

HSP27 is an ATP-independent chaperone that confers protection against apoptosis through various mechanisms, including a direct interaction with cytochrome c. Here we show that HSP27 overexpression in various cell types enhances the degradation of ubiquitinated proteins by the 26S proteasome in respo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Parcellier, Arnaud, Schmitt, Elise, Gurbuxani, Sandeep, Seigneurin-Berny, Daphné, Pance, Alena, Chantôme, Aurélie, Plenchette, Stéphanie, Khochbin, Saadi, Solary, Eric, Garrido, Carmen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC166315/
https://ncbi.nlm.nih.gov/pubmed/12897149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.16.5790-5802.2003
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