A major role for carbon monoxide as an endogenous hyperpolarizing factor in the gastrointestinal tract

Carbon monoxide (CO) is proposed as a physiological messenger. CO activates cGMP and has a direct effect on potassium channels. Both actions of CO lead to hyperpolarization of a cell's resting membrane potential, suggesting that CO may function as a hyperpolarizing factor, although direct evide...

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Bibliografiska uppgifter
Huvudupphovsmän: Farrugia, Gianrico, Lei, Sha, Lin, Xue, Miller, Steven M., Nath, Karl A., Ferris, Christopher D., Levitt, Michael, Szurszewski, Joseph H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2003
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC166269/
https://ncbi.nlm.nih.gov/pubmed/12832617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1431233100
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