Inhibition of bacterial DNA replication by zinc mobilization during nitrosative stress

Phagocytic cells inhibit the growth of intracellular pathogens by producing nitric oxide (NO). NO causes cell filamentation, induction of the SOS response, and DNA replication arrest in the Gram-negative bacterium Salmonella enterica. NO also induces double-stranded chromosomal breaks in replication...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Schapiro, Jeffrey M., Libby, Stephen J., Fang, Ferric C.
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 2003
Subjects:	Biological Sciences
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166257/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12829799/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1033133100
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