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Lytic but not latent infection by Kaposi's sarcoma-associated herpesvirus requires host CSL protein, the mediator of Notch signaling

Infection by Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is a key factor in the development of KS. Both latent and lytic KSHV infection is observed in KS tumor cells, and both genetic programs contribute importantly to KS pathogenesis. The viral replication and transcription activator (RTA)...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Liang, Yuying, Ganem, Don
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166256/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12832621/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1432843100
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