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R5 HIV productively infects Langerhans cells, and infection levels are regulated by compound CCR5 polymorphisms
Langerhans cells (LCs) are suspected to be initial targets for HIV after sexual exposure (by becoming infected or by capturing virus). Here, productive R5 HIV infection of LC ex vivo and LC-mediated transmission of virus to CD4(+) T cells were both found to depend on CCR5. By contrast, infection of...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166241/ https://ncbi.nlm.nih.gov/pubmed/12815099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1432450100 |
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