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Asymmetric localization of flotillins/reggies in preassembled platforms confers inherent polarity to hematopoietic cells

Hematopoietic cells have long been defined as round, nonpolar cells that show uniform distribution of cell surface-associated molecules. However, recent analyses of the immunological synapse and the importance of lipid microdomains in signaling have shed new light on the aspect of lymphocyte polariz...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Rajendran, Lawrence, Masilamani, Madhan, Solomon, Samuel, Tikkanen, Ritva, Stuermer, Claudia A. O., Plattner, Helmut, Illges, Harald
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166213/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12826615/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1331629100
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