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tmRNAs that encode proteolysis-inducing tags are found in all known bacterial genomes: A two-piece tmRNA functions in Caulobacter

A general mechanism in bacteria to rescue stalled ribosomes and to clear the cell of incomplete polypeptides involves an RNA species, tmRNA (SsrA), which functions as both a tRNA and an mRNA. This RNA encodes a peptide tag that is incorporated at the end of the aberrant polypeptide and targets it fo...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Keiler, Kenneth C., Shapiro, Lucy, Williams, Kelly P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16621/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10884408/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.14.7778
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