Quinupristin-Dalfopristin Resistance in Streptococcus pneumoniae: Novel L22 Ribosomal Protein Mutation in Two Clinical Isolates from the SENTRY Antimicrobial Surveillance Program

Resistance to quinupristin-dalfopristin (Q/D) among gram-positive cocci has been very uncommon. Two clinical isolates among 8,837 (0.02%) Streptococcus pneumoniae isolates were discovered in 2001 to 2002 with Q/D MICs of 4 μg/ml. Each had a 5-amino-acid tandem duplication (RTAHI) in the L22 ribosoma...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Jones, Ronald N., Farrell, David J., Morrissey, Ian
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Mechanisms of Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12878545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.8.2696-2698.2003
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