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Haemophilus influenzae bla(ROB-1) Mutations in Hypermutagenic ΔampC Escherichia coli Conferring Resistance to Cefotaxime and β-Lactamase Inhibitors and Increased Susceptibility to Cefaclor

The clinical use of cefaclor has been shown to enrich Haemophilus influenzae populations harboring cefaclor-hydrolyzing ROB-1 β-lactamase. Such a selective process may lead to the increased use of extended-spectrum cephalosporins or β-lactams plus β-lactamase inhibitors and, eventually, resistance t...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Galán, Juan-Carlos, Morosini, María-Isabel, Baquero, María-Rosario, Reig, Milagro, Baquero, Fernando
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166061/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12878518/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.8.2551-2557.2003
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