Changes in rates of upper gastrointestinal hemorrhage after the introduction of cyclooxygenase-2 inhibitors in British Columbia and Ontario

BACKGROUND: Population rates of upper gastrointestinal (GI) hemorrhage have been observed to increase with the introduction and rapid uptake of selective cyclooxygenase-2 (COX-2) inhibitors. Changes in COX-2 inhibitor use and upper GI bleeding rates in regions with relatively restrictive drug polici...

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Detalhes bibliográficos
Main Authors: Mamdani, Muhammad, Warren, Leanne, Kopp, Alex, Paterson, J. Michael, Laupacis, Andreas, Bassett, Ken, Anderson, Geoffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: Canadian Medical Association 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1660595/
https://ncbi.nlm.nih.gov/pubmed/17146090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/cmaj.050192
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