Gene expression patterns that predict sensitivity to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer cell lines and human lung tumors

BACKGROUND: Increased focus surrounds identifying patients with advanced non-small cell lung cancer (NSCLC) who will benefit from treatment with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI). EGFR mutation, gene copy number, coexpression of ErbB proteins and ligands, and e...

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Main Authors: Balko, Justin M, Potti, Anil, Saunders, Christopher, Stromberg, Arnold, Haura, Eric B, Black, Esther P
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2006
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1660550/
https://ncbi.nlm.nih.gov/pubmed/17096850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-7-289
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