Biochemical and Functional Analyses of the Mip Protein: Influence of the N-Terminal Half and of Peptidylprolyl Isomerase Activity on the Virulence of Legionella pneumophila

The virulence factor Mip (macrophage infectivity potentiator) contributes to the intracellular survival of Legionella pneumophila, the causative agent of Legionnaires' disease. The protein consists of two domains that are connected via a very long α-helix (A. Riboldi-Tunnicliffe et al., Nat. St...

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Detalhes bibliográficos
Main Authors: Köhler, Rolf, Fanghänel, Jörg, König, Bettina, Lüneberg, Edeltraud, Frosch, Matthias, Rahfeld, Jens-Ulrich, Hilgenfeld, Rolf, Fischer, Gunter, Hacker, Jörg, Steinert, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166037/
https://ncbi.nlm.nih.gov/pubmed/12874317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4389-4397.2003
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