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Induction of Specific T-Cell Responses, Opsonizing Antibodies, and Protection against Plasmodium chabaudi adami Infection in Mice Vaccinated with Genomic Expression Libraries Expressed in Targeted and Secretory DNA Vectors

It has been proposed that a multivalent malaria vaccine is necessary to mimic the naturally acquired resistance to this disease observed in humans. A major experimental challenge is to identify the optimal components to be used in such a multivalent vaccine. Expression library immunization (ELI) is...

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Detalhes bibliográficos
Main Authors: Rainczuk, A., Scorza, T., Smooker, P. M., Spithill, T. W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166036/
https://ncbi.nlm.nih.gov/pubmed/12874330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4506-4515.2003
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