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Production of resistant HIV mutants during antiretroviral therapy

HIV drug therapy often fails because of the appearance of multidrug-resistant virus. There are two possible scenarios for the outgrowth of multidrug-resistant virus in response to therapy. Resistant virus may preexist at low frequencies in drug-naïve patients and is rapidly selected in the presence...

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Detalhes bibliográficos
Main Authors: Ribeiro, Ruy M., Bonhoeffer, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16603/
https://ncbi.nlm.nih.gov/pubmed/10884399
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