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The Absence of Linear Plasmid 25 or 28-1 of Borrelia burgdorferi Dramatically Alters the Kinetics of Experimental Infection via Distinct Mechanisms

The 25-kb linear plasmid lp25 and one of the 28-kb linear plasmids (lp28-1) are required for experimental infection in Borrelia burgdorferi, the etiologic agent of Lyme disease. The loss of these plasmids either eliminates infectivity (lp25) or significantly increases the 50% infective dose during a...

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Autori principali: Labandeira-Rey, Maria, Seshu, J., Skare, Jonathan T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC166013/
https://ncbi.nlm.nih.gov/pubmed/12874340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4608-4613.2003
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