Genome-Based Bioinformatic Selection of Chromosomal Bacillus anthracis Putative Vaccine Candidates Coupled with Proteomic Identification of Surface-Associated Antigens

Bacillus anthracis (Ames strain) chromosome-derived open reading frames (ORFs), predicted to code for surface exposed or virulence related proteins, were selected as B. anthracis-specific vaccine candidates by a multistep computational screen of the entire draft chromosome sequence (February 2001 ve...

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Autors principals: Ariel, N., Zvi, A., Makarova, K. S., Chitlaru, T., Elhanany, E., Velan, B., Cohen, S., Friedlander, A. M., Shafferman, A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Molecular Genomics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC165985/
https://ncbi.nlm.nih.gov/pubmed/12874336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4563-4579.2003
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