Simultaneous Blocking of Human Toll-Like Receptors 2 and 4 Suppresses Myeloid Dendritic Cell Activation Induced by Mycobacterium bovis Bacillus Calmette-Guérin Peptidoglycan

The Mycobacterium bovis bacillus Calmette-Guérin (BCG) cell wall skeleton (CWS) consists of mycolic acids, arabinogalactan, and peptidoglycan (PGN) and activates Toll-like receptor 2 (TLR2) and TLR4. Here we investigated the ability of the essential portion of highly purified BCG CWS to support the...

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Autores principales: Uehori, Junji, Matsumoto, Misako, Tsuji, Shoutaro, Akazawa, Takashi, Takeuchi, Osamu, Akira, Shizuo, Kawata, Tsutomu, Azuma, Ichiro, Toyoshima, Kumao, Seya, Tsukasa
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Host Response and Inflammation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC165983/
https://ncbi.nlm.nih.gov/pubmed/12874299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4238-4249.2003
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