Processing of DNA lesions by archaeal DNA polymerases from Sulfolobus solfataricus

Spontaneous damage to DNA as a result of deamination, oxidation and depurination is greatly accelerated at high temperatures. Hyperthermophilic microorganisms constantly exposed to temperatures exceeding 80°C are endowed with powerful DNA repair mechanisms to maintain genome stability. Of particular...

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Huvudupphovsmän: Grúz, Petr, Shimizu, Masatomi, Pisani, Francesca M., Felice, Mariarita De, Kanke, Yusuke, Nohmi, Takehiko
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2003
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC165962/
https://ncbi.nlm.nih.gov/pubmed/12853619
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