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Mitochondria-mediated nuclear mutator phenotype in Saccharomyces cerevisiae

Using Saccharomyces cerevisiae as a model organism, we analyzed the consequences of disrupting mitochondrial function on mutagenesis of the nuclear genome. We measured the frequency of canavanine-resistant colonies as a measure of nuclear mutator phenotype. Our data suggest that mitochondrial dysfun...

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Autors principals: Rasmussen, Anne Karin, Chatterjee, Aditi, Rasmussen, Lene Juel, Singh, Keshav K.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC165961/
https://ncbi.nlm.nih.gov/pubmed/12853606
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