The hSK4 (KCNN4) isoform is the Ca(2)(+)-activated K(+) channel (Gardos channel) in human red blood cells

The question is, does the isoform hSK4, also designated KCNN4, represent the small conductance, Ca(2)(+)-activated K(+) channel (Gardos channel) in human red blood cells? We have analyzed human reticulocyte RNA by RT-PCR, and, of the four isoforms of SK channels known, only SK4 was found. Northern b...

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Bibliographic Details
Main Authors: Hoffman, Joseph F., Joiner, William, Nehrke, Keith, Potapova, Olga, Foye, Kristen, Wickrema, Amittha
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC165881/
https://ncbi.nlm.nih.gov/pubmed/12773623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1232342100
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