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Targeted mutation of the outer membrane protein P66 disrupts attachment of the Lyme disease agent, Borrelia burgdorferi, to integrin α(v)β(3)

Borrelia burgdorferi, the agent of Lyme disease, expresses several adhesion molecules that are probably required for initial establishment of infection in mammalian hosts, and for colonization of various tissues within the host. The B. burgdorferi outer membrane protein P66 was previously identified...

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Bibliographic Details
Main Authors: Coburn, Jenifer, Cugini, Carla
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC165870/
https://ncbi.nlm.nih.gov/pubmed/12748384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1131117100
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