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Cytosine Methylation by the SuaI Restriction-Modification System: Implications for Genetic Fidelity in a Hyperthermophilic Archaeon
5-Methylcytosine in chromosomal DNA represents a potential source of frequent spontaneous mutation for hyperthermophiles. To determine the relevance of this threat for the archaeon Sulfolobus acidocaldarius, the mode of GGCC methylation by its restriction-modification system, SuaI, was investigated....
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2003
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165766/ https://ncbi.nlm.nih.gov/pubmed/12867480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.15.4657-4661.2003 |
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