The Yeast Eukaryotic Initiation Factor 4G (eIF4G) HEAT Domain Interacts with eIF1 and eIF5 and Is Involved in Stringent AUG Selection

Eukaryotic initiation factor 4G (eIF4G) promotes mRNA recruitment to the ribosome by binding to the mRNA cap- and poly(A) tail-binding proteins eIF4E and Pap1p. eIF4G also binds eIF4A at a distinct HEAT domain composed of five stacks of antiparallel α-helices. The role of eIF4G in the later steps of...

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Bibliografiske detaljer
Main Authors: He, Hui, von der Haar, Tobias, Singh, C. Ranjit, Ii, Miki, Li, Bin, Hinnebusch, Alan G., McCarthy, John E. G., Asano, Katsura
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC165723/
https://ncbi.nlm.nih.gov/pubmed/12861028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.15.5431-5445.2003
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