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An improved and highly sensitive microfluorimetric method for assessing susceptibility of Plasmodium falciparum to antimalarial drugs in vitro

BACKGROUND: The standard in vitro protocol currently in use for drug testing against Plasmodium falciparum, based on the incorporation of the purine [(3)H]-hypoxanthine, has two serious drawbacks. Firstly it is unsuitable for the testing of drugs that directly or indirectly impact on purine salvage...

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Detalhes bibliográficos
Main Authors: Quashie, Neils B, de Koning, Harry P, Ranford-Cartwright, Lisa C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1657019/
https://ncbi.nlm.nih.gov/pubmed/17076900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-5-95
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