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Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex

The sec6/8 complex or exocyst is an octameric protein complex that functions during cell polarization by regulating the site of exocytic vesicle docking to the plasma membrane, in concert with small GTP-binding proteins. The Sec5 subunit of the mammalian sec6/8 complex binds Ral in a GTP-dependent m...

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Hlavní autoři: Fukai, Shuya, Matern, Hugo T., Jagath, Junutula R., Scheller, Richard H., Brunger, Axel T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC165653/
https://ncbi.nlm.nih.gov/pubmed/12839989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg329
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