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A recessive mutant of Drosophila Clock reveals a role in circadian rhythm amplitude

The transcription factor Clock (Clk) plays a critical role in animal circadian rhythms. Genetic studies defining its function have relied on two dominant negative alleles, one in Drosophila and one in mice. Here we describe a novel recessive allele of Drosophila Clock, Clk(ar). Homozygous Clk(ar) fl...

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Detalhes bibliográficos
Main Authors: Allada, Ravi, Kadener, Sebastian, Nandakumar, Namrata, Rosbash, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165643/
https://ncbi.nlm.nih.gov/pubmed/12839998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg318
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