Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression

Hox proteins are transcription factors involved in controlling axial patterning, leukaemias and hereditary malformations. Here, we show that HOXC10 oscillates in abundance during the cell cycle, being targeted for degradation early in mitosis by the ubiquitin-dependent proteasome pathway. Among abdo...

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Détails bibliographiques
Auteurs principaux: Gabellini, Davide, Colaluca, Ivan N., Vodermaier, Hartmut C., Biamonti, Giuseppe, Giacca, Mauro, Falaschi, Arturo, Riva, Silvano, Peverali, Fiorenzo A.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2003
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC165610/
https://ncbi.nlm.nih.gov/pubmed/12853486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg340
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