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Multiple differences in gene expression in regulatory Vα24JαQ T cells from identical twins discordant for type I diabetes

Quantitative and qualitative defects in CD1d-restricted T cells have been demonstrated in human and murine autoimmune diseases. To investigate the transcriptional consequences of T cell receptor activation in human Vα24JαQ T cell clones, DNA microarrays were used to quantitate changes in mRNA levels...

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Detalhes bibliográficos
Main Authors: Wilson, S. Brian, Kent, Sally C., Horton, Heidi F., Hill, Andrew A., Bollyky, Paul L., Hafler, David A., Strominger, Jack L., Byrne, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16559/
https://ncbi.nlm.nih.gov/pubmed/10840051
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